Table 1.
Baseline demographic and clinical characteristics of the study participants
| All Subjects N = 77 |
|
|---|---|
| Age at initial diagnosis (yr), mean (SD) | 4.3 (3.9) |
| Age at specimen collection (yr), mean (SD) | 13.9 (4.9) |
| Female sex, n (%) | 39 (51) |
| Race, n (%) | |
| White | 63 (82) |
| Asian | 9 (12) |
| Other/unknown | 5 (6) |
| Growth parameters, mean (SD) | n = 70* |
| Height percentile | 47.5 (29.7) |
| Weight percentile | 55.3 (30.2) |
| Body mass index percentile | 56.4 (31.8) |
| Clinical features, n (%) | |
| Neonatal respiratory distress | 63 (82) |
| Situs inversus/laterality defect | 38 (49) |
| Chronic otitis media | 73 (95) |
| Chronic nasal congestion | 75 (97) |
| Chronic cough | 75 (97) |
| FEV1% predicted, mean (SD) | 80.8 (20.5) |
| Respiratory culture results, n (%) | |
| Haemophilus influenzae | 14 (18) |
| Staphylococcus aureus | 22 (29) |
| Streptococcus pneumoniae | 9 (12) |
| Moraxella catarrhalis | 2 (3) |
| Pseudomonas aeruginosa | 3 (4) |
| No pathogenic bacteria detected | 39 (51) |
| One pathogenic bacterium detected | 27 (35) |
| Two or more pathogenic bacteria detected | 11 (14) |
| Medications, n (%) | |
| Azithromycin | 18 (23) |
| Hypertonic saline | 18 (23) |
| Dornase alfa | 9 (12) |
| Inhaled corticosteroids | 42 (55) |
Definition of abbreviations: FEV1 = forced expiratory volume in 1 second; SD = standard deviation.
*
Percentiles are provided for subjects less than 20 yr old at their study visit.