Table 4.

Risk of depression in stroke survivors and control group according to age and sex.

		N	Depression Event	IR (per 1000 PYs)	aHR (95% CI)	p for Interaction
By age
Age < 65	Control	137,526	14,432	20.93	1 (ref.)	<0.001
	No disability after stroke	87,533	24,556	76.36	2.72(2.66–2.78)
	Mild disability after stroke	5511	2237	109.39	3.66 (3.50–3.83)
	Severe disability after stroke	3323	1669	170.62	5.39 (5.12–5.67)
Age ≥ 65	Control	156,980	35,148	46.76	1 (ref.)
	No disability after stroke	97,650	32,944	111.75	1.76 (1.73–1.79)
	Mild disability after stroke	9194	3940	133.6	2.04 (1.98–2.12)
	Severe disability after stroke	4467	2124	176.58	2.62 (2.51–2.74)
		N	Depression Event	IR (per 1000 PYs)	aHR (95% CI)	p for Interaction
By sex
Male	Control	182,928	25,659	28.49	1 (ref.)	<0.001
	No disability after stroke	115,021	32,899	83.95	2.19 (2.15–2.23)
	Mild disability after stroke	9532	3734	113.65	2.73 (2.63–2.83)
	Severe disability after stroke	5121	2401	164.12	3.78 (3.62–3.95)
Female	Control	111,578	23,921	44.24	1 (ref.)
	No disability after stroke	70,162	24,601	109.58	1.89 (1.86–1.93)
	Mild disability after stroke	5173	3734	142.99	2.16 (2.07–2.25)
	Severe disability after stroke	2669	2401	193.84	2.92 (2.76–3.08)

aHRs were adjusted for age, sex, CCI, place, income, DM, HTN, dyslipidemia, smoking, alcohol consumption, and exercise. Abbreviations: IR, incidence rate; PYs, person-years; aHR, adjusted hazard ratio; CI, confidence interval; CCI, Charlson Comorbidity Index.