Table 2.
Comparison of cytotoxicity (IC50) of the tested compounds against BALB/3T3 cell line depending on the dicarboxylic linker and amine present in their structure.
| R2 |
|
|
|
|
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R1 | |||||||||||||||
|
2 (53.37) | 2b (25.04) | 2d (50.00) | 2a (3.10) | 2c (32.71) | ||||||||||
|
3 (37.17) | 3b (24.69) | 3d (50.00) | ||||||||||||
|
4 (37.90) | 4b (36.76) | 4d (50.00) | 4a (5.02) | |||||||||||
|
5 (23.44) | 5b (20.36) | |||||||||||||
| Betulin 1 (31.79) | |||||||||||||||
| Doxorubicin (0.18) | |||||||||||||||
| Scale: | 1 | 2 | 5 | 10 | 15 | 25 | 31.79 | 40 | 45 | 50 | |||||
The color scheme visualizes active compounds in green and inactive ones in red. Color saturation corresponds to their degree of activity as indicated on the scale.