Abbreviation	Definition
µCT	Microcomputed tomography
2D	Two-dimensional
3D	Three-dimensional
4-PBA	4-phenylbutyrate
N-terminal	Amino- terminal
ActRIIB	Activin receptor type IIB
ATP	Adenosine triphosphate
BM	Bone Marrow
BMD	Bone mineral density
BPs	Bisphosphonates
C-terminal	Carboxyl- terminal
CTX	Carboxyl-terminal cross-linking telopeptide of type I collagen
ECM	Extracellular matrix
ELISA	Enzyme-linked immunoassay
ER	Endoplasmic reticulum
EVs	Extracellular vesicles
FPP	Farnesyl Pyrophosphate
GFP	Green fluorescent protein
hfMSCs	Human fetal blood MSCs
ISR	Integrated stress response
IUT	In utero transplantation
LH2	Lysyl hydroxylase 2
LRP	Low density lipoprotein receptor-related protein
mAb	Monoclonal Antibody
MSCs	Mesenchymal stem cells
NGS	Next-generation sequencing
OI	Osteogenesis Imperfecta
OST	Osteocalcin
PGE2	Prostaglandin E2
RANKL	Receptor activator of nuclear factor kappa beta ligand
RNA	Ribonucleic acid
Scl-Ab	Anti-sclerostin antibody
SDF1	Stromal cell-derived factor 1
TGF-β	Transforming growth factor beta
TRAP	Tartrate-resistant acid phosphatase
WNT	Wingless-related integration site
WT	Wild type
YAP	Yes-associated protein