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. 2022 Dec 9;2022(1):450-458. doi: 10.1182/hematology.2022000380

Table 2.

Differences between ischemic and nonischemic priapism

Characteristic Ischemic Nonischemic
Pain A common feature Not a common feature
Erection hardness Rigid with the soft glans penis Not rigid
Trauma No associated history of penile trauma Trauma or penile surgical procedure is a common feature
Medical conditions and drugs Commonly associated with SCD, other hematologic disorders, snake and scorpion venoms, alcohol, recreational drugs, or medications Not associated with any medical condition, except as a complication of penile surgical interventions
Pattern Recurrent Not recurrent
Blood aspirate color Dark Bright red
Blood gas analysis PO2 <30  mm Hg, PCO2 >60  mm Hg, pH <7.25 PO2 >90  mm Hg, PCO2 <40  mm Hg, pH 7.4
Ultrasound color Doppler scan Low arterial flow
Fibrosis can be identified
High arterial flow
No fibrosis
Acute treatment strategies Supportive care, corporal aspiration, and surgical shunt Conservative management, arterial embolization, and surgical ligation
Secondary prevention Needed in recurrent events Not required
Penile implantation May be required when associated with erectile dysfunction Unlikely to be required.

PCO2, partial pressure of carbon-dioxide; PO2, partial pressure of oxygen.