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. 2022 Dec 28;24(1):499. doi: 10.3390/ijms24010499

Figure 1.

Figure 1

Several invadosome-associated genes are increased in lungs from IPF patients. Heatmaps of differential expression analysis using public datasets. Expression levels are presented as Z-scores. Significance of each gene is shown on the left with Benjamini–Hochberg false discovery rate adjusted p-values. Gene expression in lung tissue from GSE32537 of (A) 6 fibrosis-associated genes and (B) 17 genes encoding proteins involved in invadosome formation. Ctrl (n = 50) and IPF (n = 119). (C) Gene expression from GSE169500 of 10 genes involved in invadosome formation. Control alveolar septae (n = 10), IPF alveolar septae (n = 10) and IPF fibroblastic foci (n = 10). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.