ALS |
Amyotrophic Lateral Sclerosis |
β-End 1–31 |
β-endorphin 1–31 |
BD1047 |
N′-[2-(3,4-dichlorophenyl)ethyl]-N,N,N′-trimethylethane-1,2-diamine;dihydrobromide |
BD1063 |
1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine |
BiP |
78-kDa glucose-regulated binding protein (GRP78) |
CCI |
Unilateral sciatic nerve chronic contrition injury |
CHO |
Chinese hamster ovarian cells |
CNS |
Central nervous system |
DADLE |
([D-Ala2, D-Leu5]-Enkephalin |
D-Ala2 Deltorphin II |
Tyr-D-Ala-Phe-Glu-Val-Val-Gly amide |
DAMGO |
([D-Ala2, N-MePhe4, Gly-ol]-enkephalin |
DOR |
Delta-opioid receptor |
DPDPE |
([D-Pen2,D-Pen5]enkephalin) |
ε |
Epsilon receptor |
EC50 |
Efficacious concentration to reduce 50% a given effect |
ER |
Endoplasmic reticulum |
HINT1 |
Histidine triad nucleotide binding protein 1 |
GPCR |
G-protein-coupled receptor |
Icv |
Intracerebroventricular |
KOR |
Kappa-opioid receptor |
MOR |
Mu-opioid receptor |
αN-acetyl |
Acetylated β-End N terminal Y1, α position |
NMDA |
N-methyl-d-aspartate acid |
NMDAR |
N-methyl-d-aspartate acid glutamate receptor |
PAG |
Periaqueductal grey matter |
pMCAO |
Permanent unilateral middle cerebral artery occlusion |
POMC |
Proopiomelanocortin |
(+/−)PPCC |
(1R,2S/1S,2R)-2-[4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl) cyclopropanecarboxylate |
PRE084 |
2-(4-morpholinethyl)-1-phenylcyclohexanecarboxylate hydrochloride |
PTX |
Pertussis toxin |
RVD |
Rat vas deferens |
σ1R |
Type 1 sigma receptor |
σ2R |
Type 2 sigma receptor |
SBM |
Solubilized brain membranes enriched in synaptosomes |
SKF-10,047 |
(2S,6S,11S)-3-Allyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocine-8-ol |
U-50,488H |
Trans-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzeneacetamide |
WT |
Wild-type |