Table 2.

Factors to be considered when choosing induction therapy

Patient related	Disease related	Treatment related
Age/Fitness	Bone marrow disease burden	Access to standard-of-care therapies
Caregiver support	Extramedullary disease	Costs and copays
Comorbidities	Molecular cytogenetics/genomics	Route of administration
Compliance	CRAB symptoms	Clinical trial availability
Lifestyle preferences	R-ISS/ISS	Toxicity
Performance status/Frailty

ISS, International Staging System; R-ISS, Revised International Staging System.