Table 2.

The examples of cardiovascular diseases animal models.

Medical Condition	Strain	Phenotype Occurrence or Induction	Reference
	ApoE −/− mice	display delayed lipoprotein clearance and develop dyslipoproteinemia, hypercholesterolemia and atherosclerotic lesions even when fed normal chow	[37,38]
	LDRL −/− mice	fed normal chow develop atherosclerosis gradually, can be accelerated on a high-fat diet, hyperlipidemia with human-like profile	[37,39]
	OPG −/− mice	exhibit an unexpected increase in vascular calcification in the aorta and renal arteries	[40]
	Lewis rats	immunisation with porcine cardiac myosin fraction	[41,42]
	C3H mice (Harlan)	viral myocarditis with Coxsackie virus B3 (CVB3)	[43]
Myocardial infarction and perfusion	C57BL/6J mice	coronary artery ligation	[44]
Ischemia-reperfusion	Sprague Dawley rats	development of an ischemia-reperfusion injury, temporal coronary artery ligation for 30 min followed by a 120 min reperfusion	[45,46]