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. 2022 Dec 21;24(1):56. doi: 10.3390/ijms24010056

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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rHuCXCL13 induces the development of BPH in vivo. (A) Concentration of inflammation markers in rat blood. (B) Relative mRNA expression of inflammation markers in rat prostate tissues. (C) Western blot assay of cell-cycle- and EMT-related proteins in sham and rHuCXCL13-treated rat prostate tissues. (D) Relative densitometric quantification of cell-cycle- and EMT-related proteins in sham and rHuCXCL13-treated rat prostate tissues. (E) Western blot assay of fibrosis- and inflammation-related proteins in sham and rHuCXCL13-treated rat prostate tissues. (F) Relative densitometric quantification of fibrosis- and inflammation-related proteins in sham and rHuCXCL13-treated rat prostate tissues. * p < 0.05, ** p < 0.01, *** p < 0.001 and ns means no significant difference.