Table 3.
Morphokinetic parameters of 681 embryos obtained after ICSI according to the occurrence of live birth and sperm chromatin condensation state.
| Parameters (Hours) |
Total Cohort (n = 681 Embryos) |
Live Birth | p | NSCC (n = 603) |
ASCC (n = 78) |
p | |
|---|---|---|---|---|---|---|---|
| Yes (n = 276) | No (n = 405) | ||||||
| tPB2 | 3.3 [2.8; 3.9] | 3 [3; 4] | 3 [3; 4] | 0.86 | 3.3 [2.8; 4] | 3.3 [2.9; 3.6] | 0.5 |
| tPNa | 7.2 [6.3; 8.2] | 7.2 [6.4; 8.1] | 7.3 [6.3; 17.2] | 0.86 | 7.3 [6.3; 8.3] | 6.8 [6.4; 7.6] | 0.2 |
| tPNf | 23.6 [22.2; 25.3] | 23.6 [22.2; 25.7] | 23.6 [22.1; 25.3] | 0.89 | 23.8 [22.4; 25.6] | 22.6 [21.3; 23.7] | 0.03 |
| t2 | 26.2 [24.8; 28.1] | 26.6 [24.6; 25] | 26.1 [25; 27.8] | 0.63 | 26.6 [25.2; 28.3] | 25.3 [23.8; 26.5] | 0.02 |
| t3 | 36.7 [34.5; 39.2] | 36.78 [34.4; 39] | 36.72 [34.5; 39.3] | 0.80 | 36.9 [34.5; 39.4] | 35.3 [33.7; 36.8] | 0.08 |
| t4 | 38.2 [34.5; 39.2] | 38.1 [35.6; 40.1] | 38.2 [35.9; 40.4] | 0.79 | 38.4 [36; 40.5] | 36.2 [25.5; 38.1] | 0.05 |
| ECC1 | 22.8 [21.4; 24.3] | 23 [21.2; 24.7] | 22.7 [21.4; 24] | 0.65 | 23.5 [21.5; 24.3] | 22.2 [20.5; 22.8] | 0.02 |
| ECC2 | 11.7 [10.7; 12.9] | 11.69 [10.8; 12.8] | 11.8 [10.7; 23.2] | 0.69 | 11.2 [1.7; 12.9] | 11.7 [11.6; 12.4] | 0.6 |
| S2 | 1.2 [0.6; 2.5] | 1.08 [0.6; 2.2] | 1.24 [0.63; 2.8] | 0.44 | 2.5 [0.6; 2.7] | 1.8 [0.7; 1.2] | 0.5 |
| S-phase length | 16.4 [15; 18] | 16.32 [15; 18.51] | 16.39 [15; 17.9] | 0.82 | 16.8 [15.1; 18] | 16.1 [14.4; 16.8] | <0.001 |
For continuous variables, median and quartiles 1 (Q1) and 3 (Q3) are presented. A p-value of <0.05 is considered significant. ASCC: abnormal sperm chromatin condensation; n: population size; NSCC: normal sperm chromatin condensation; sd: standard deviation.