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. 2022 Dec 24;24(1):291. doi: 10.3390/ijms24010291

Figure 8.

Figure 8

Representative images of the inner hair cells and their synapses corresponding to the 16 kHz region. Hair cells are labeled for myosin VIIa (blue), presynaptic ribbons for CtBP2 (red) and the postsynaptic density is labeled green. Yellow dots indicate an overlapping and therefore a colocalization of the CtBP2 and the PSD95 staining. Doted lines show the contour of a single IHC. Arrows point at synapses with colocalized staining. Left pictures (A,D,G,J) show only the CtBP2 staining and pictures in the middle only the PSD95 staining (B,E,H,K). The right pictures (C,F,I,L) display an overlay of all stainings. (A–C) belong to an implanted ear treated with IGF-1. (D–F) show a contralateral ear of an IGF-1 treated animal. (G–I) belong to an implanted ear treated with AP and (J–L) belong to a contralateral ear of an AP treated animal. Scale bars indicate 5 µm.