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Effects of isorhamnetin treatment in mutant nematodes lacking lipid metabolism related genes.
| Lacking Gene | Related Alteration | Effect |
|---|---|---|
| Sbp-1 | Lipogenesis | ↓TG |
| Tub-1 | Lipogenesis | ↓TG |
| Nhr-49 | b-oxidation, lipolysis | NS |
| Aak-2 | Energy metabolism | ↓TG |
| Aak-1 and Aak-2 | Energy metabolism | ↓TG |
Aak: AMP-activated kinase; Nhr-49: nuclear hormone receptor 49; Sbp-1: sterol regulatory element binding protein 1; TG: triglyceride; Tub-1: ortholog of the mammalian TUBBY 1.
