Table 2.
Correlation between inflammatory indexes and clinical-pathological features in patients with colorectal carcinoma.
| VARIABLES | INFLAMMATION INDEXEX | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AISI | SII | SIRI | MLR | MPR | NLPR | NLR | dNLR | PLR | HGB/RDW | ||||||||||||
| Median (IQR) | p Value | Median (IQR) | p Value | Median (IQR) | p Value | Median (IQR) | p Value | Median (IQR) | p Value | Median (IQR) | p Value | Median (IQR) | p Value | Median (IQR) | p Value | Median (IQR) | p Value | Media ± SD | p Value | ||
| Gender | |||||||||||||||||||||
| Female. n (%) | 17 (34.0) | 275.3 (122.7–506.4) | 0.749 | 641.0 (502.0–1266.1) | 0.447 | 0.9 (0.5–2.1) | 0.540 | 0.2 (0.2–0.4) | 0.141 | 0.03 (0.02–0.03) | 0.152 | 0.01 (0.01–0.01) | 0.103 | 2.4 (2.0–3.3) | 0.713 | 1.8 (1.3–2.4) | 0.500 | 165.1 (131.8–238.9) | 0.254 | 0.8 ± 0.2 | 0.878 |
| Male. n (%) | 33 (66.0) | 323.1 (154.5–537.3) | 663.0 (401.8–884.2) | 1.4 (0.7–2.0) | 0.3 (0.2–0.5) | 0.04 (0.02–0.05) | 0.01 (0.01–0.02) | 2.6 (2.1–3.5) | 1.7 (1.4–2.2) | 154.7 (107.8–200.6) | 0.8 ± 0.2 | ||||||||||
| Age at diagnosis | |||||||||||||||||||||
| < 65 years. n (%) | 19 (38.0) | 319.7 (156.00–584.9) | 0.417 | 673.5 (502.0–1266.1) | 0.391 | 1.2 (0.7–2.7) | 0.659 | 0.2 (0.2–0.6) | 0.643 | 0.03 (0.02–0.04) | 0.730 | 0.01 (0.01–0.02) | 0.968 | 2.7 (1.8–5.6) | 0.826 | 1.7 (1.3–2.8) | 0.586 | 166.9 (122.7–238.9) | 0.502 | 0.8 ± 0.3 | 0.983 |
| ≥ 65 years. n (%) | 31 (62.0) | 293.8 (108.43–475.7) | 644.3 (401.8–884.2) | 1.2 (0.7–1.7) | 0.3 (0.2–0.4) | 0.03 (0.02–0.04) | 0.01 (0.01–0.02) | 2.4 (2.2–3.5) | 1.7 (1.4–2.1) | 154.7 (112.1–204.8) | 0.8 ± 0.2 | ||||||||||
| Site | |||||||||||||||||||||
| Left. n (%) | 35 (70.0) | 241.0 (114.5–446.6) | 0.058 | 595.0 (393.8–795.1) | 0.095 | 1.1 (0.6–2.1) | 0.461 | 0.3 (0.2–0.5) | 0.760 | 0.04 (0.03–0.04) | 0.002 | 0.01 (0.01–0.02) | 0.087 | 2.6 (2.0–3.8) | 0.867 | 1.7 (1.4–2.3) | 0.956 | 145.2 (104.9–185.6) | 0.020 | 0.9 ± 0.2 | <0.001 |
| Right. n (%) | 12 (24.0) | 446.5 (277.0–589.4) | 857.7 (520.0–1227.7) | 1.2 (1.1–1.7) | 0.3 (0.3–0.4) | 0.02 (0.02–0.03) | 0.01 (0.01–0.01) | 2.3 (2.2–3.3) | 1.7 (1.4–2.2) | 201.3 (181.5–235.9) | 0.6 ± 0.2 | ||||||||||
| Histologic grade | |||||||||||||||||||||
| G1-G2. n (%) | 39 (76.5) | 300.9 (136.1–509.3) | 0.590 | 673.5 (419.9–875.4) | 0.67 | 1.2 (0.7–2.1) | 0.702 | 0.3 (0.2–0.5) | 0.307 | 0.03 (0.03–0.04) | 0.120 | 0.01 (0.01–0.02) | 0.016 | 2.7 (2.1–3.8) | 0.712 | 1.7 (1.3–2.3) | 0.967 | 161.1 (122.2–203.7) | 0.629 | 0.8 ± 0.2 | 0.194 |
| G3. n (%) | 10 (19.6) | 323.1 (174.3–559.2) | 592.1 (480.0–1213.5) | 1.2 (0.6–1.7) | 0.3 (0.2–0.4) | 0.03 (0.02–0.03) | 0.01 (0.01–0.01) | 2.3 (2.1–3.1) | 1.6 (1.5–2.1) | 162.7 (127.4–244.2) | 0.7 ± 0.2 | ||||||||||
| Tumor stage | |||||||||||||||||||||
| 0-I-II. n (%) | 24 (47.1) | 300.9 (149.4–446.5) | 0.302 | 630.5 (466.3–819.7) | 0.360 | 1.2 (0.7–1.7) | 0.481 | 0.3 (0.2–0.4) | 0.324 | 0.03 (0.03–0.04) | 0.961 | 0.01 (0.01–0.02) | 0.467 | 2.5 (2.2–3.5) | 0.549 | 1.6 (1.4–2.1) | 0.467 | 160.4 (128.8–198.5) | 0.751 | 0.8 ± 0.2 | 0.398 |
| III-IV. n (%) | 24 (47.1) | 351.0 (156.0–600.4) | 707.6 (474.1–1196.0) | 1.3 (0.7–2.1) | 0.3 (0.2–0.7) | 0.03 (0.02–0.04) | 0.01 (0.01–0.02) | 2.9 (2.1–5.3) | 1.7 (1.4–2.4) | 170.5 (122.7–238.9) | 0.8 ± 0.3 | ||||||||||
SD: standard deviation; IQR: interquartile range; AISI: aggregate index of systemic inflammation; SII: systemic immune-inflammation index; SIRI: systemic inflammation response index; MLR: monocyte to lymphocyte ratio; MPR: mean platelet volume to platelet ratio; NLPR: neutrophil to lymphocyte × platelet ratio; NLR: neutrophil to lymphocyte ratio; dNLR: derived neutrophil to lymphocyte ratio; PLR: platelet to lymphocyte ratio; HGB/RDW: hemoglobin to red cell distribution width ratio.