Table 3.
Levels of plasma polyamines and related amino acids (arginine and lysine) in patients with colorectal carcinoma and healthy people.
| Polyamine | Cancer Patients | Healthy Patients | p-Value |
|---|---|---|---|
| Agmatine | 24.1 ± 2.6 | 77.2 ± 14.5 | p < 0.001 |
| Arginine | 7.6 ± 0.6 | 6.4 ± 1.7 | p < 0.001 |
| Cadaverine | 14.2 ± 1.7 | 2.5 ± 1.1 | p < 0.001 |
| Lysine | 1.1 (1.0–1.1) | 0.7 (0.4–1.1) | p < 0.001 |
| Ornithine | 2.6 (2.6–2.7) | 0.9 (0.6 −1.4) | p < 0.001 |
| Putrescine | 17.7 (16.9–18.7) | 6.4 (5.6–7.1) | p < 0.001 |
| Acetylputrescine | 289.4 (279.3–299.5) | 0.3 (0.2–0.6) | p < 0.001 |
| Spermidine | 129.2 (124.9–135.3) | 0.9 (0.8–1.0) | p < 0.001 |
| Acetylspermidine | 10.3 (8.9–11.8) | 0.4 (0.3–0.7) | p < 0.001 |
| Spermine | 7.0 ± 1.8 | 5.9 ± 2.1 | p = 0.005 |
| Acetylspermine | 14.7 ± 1.3 | 2.3 ± 1.0 | p < 0.001 |
Agmatine, arginine, cadaverine, spermine, and acetylspermine are reported as mean ± standard deviation and analyzed using the Student–Newman–Keuls test. All other values are reported as median and interquartile range (IQR) and analyzed using the Kruskal–Wallis test. A p-value < 0.05 is considered to be statistically significant.