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. 2022 Dec 22;24(1):169. doi: 10.3390/ijms24010169

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The epidemiological data of HFMD. (a) The number of HFMD cases in China from 2008 to 2021 and the ranking of its morbidity among C infectious diseases. The data in the figure are cited from www.chinacdc.cn (accessed on 10 October 2022). (b) The fatality rate of HFMD in China from 2008 to 2021 and its ranking among category C infectious diseases. The data in the figure are cited from www.chinacdc.cn (accessed on 10 October 2022). (c) The rate of severe HFMD illnesses before and after the first inactivated EV-A71 vaccine was approved in China. The data in the figure are cited from [23]. (d) Seropositivity rates of different HFMD-associated enteroviruses in Vietnam and Korea. The data in the figure are cited from [24,25].