Table 1.

Rate (prevalence) ratio of late cardiovascular disease among acute lymphoblastic leukemia survivors (n = 6148) from the Childhood Cancer Survivor Study by treatment group

Treatment group	Heart failure, RR (95% CI)	Coronary artery disease, RR (95% CI)	Stroke, RR (95% CI)
1970s	1.0 (Ref)	1.0 (Ref)	1.0 (Ref)
1980s high risk	0.9 (0.3-2.5)	1.1 (0.3-3.3)	0.6 (0.2-1.7)
1980s standard risk	0.6 (0.2-1.6)	0.6 (0.2-1.8)	1.5 (0.7-3.2)
1990s high risk	0.4 (0.1-2.0)	0.0 (0.0-0.02)*	1.1 (0.4-3.6)
1990s standard risk	0.0 (0.0-0.1)*	0.5 (0.2-1.5)	0.4 (0.1-0.9)

From Dixon et al.⁷

^* No events reported for these groups.

CI, confidence interval; RR, relative risk.