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. 2022 Dec 23;12(1):120. doi: 10.3390/jcm12010120

Table 2.

Lugano and Paris staging systems for gastrointestinal lymphomas [29,30].

Stage Lugano System Paris System Tumor Extension
I Tumor confined to GI tract (single, primary site or multiple, noncontiguous lesions) T1m N0 M0 Mucosa
T1sm N0 M0 Submucosa
T2 N0 M0 Muscularis propria
T3 N0 M0 Serosa
II Tumor extending into abdomen NA NA
II1 Local nodal involvement T1–3 N1 M0 Perigastric lymph nodes
II2 Distant nodal involvement T1–3 N2 M0 More distant regional lymph nodes
IIE Perforation of serosa to involve adjacent organs or tissues T4 N0–2 M0 Invasion of adjacent structures with or without invasion of abdominal lymph nodes
IV Disseminated extranodal involvement or concomitant supradiaphragmatic nodal involvement T1–4 N3 M0 Extra-abdominal lymph nodes
T1–4 N0–3 M1 and/or additional distant GI/non-GI sites
T1–4 N0–3 M2 BM not assessed
T1–4 N0–3 M0–2 BX BM not involved
T1–4 N0–3 M2 B1 BM involvement

BM: bone marrow; GI: gastrointestinal; NA: not available.