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. 2022 Dec 29;12(1):251. doi: 10.3390/jcm12010251

Table 1.

The World Health Organization 2017 classification for neuroendocrine neoplasms.

NET-G1 NET-G2 NET-G3 NEC-G3
Well-differentiated
Mitotic count < 2/2 mm2
Ki-67 ≤ 2%
Well-differentiated
Mitotic count < 2–20/2 mm2
Ki-67 3–20%
Well-differentiated
Mitotic count > 20/2 mm2
Ki-67 > 20%
Poorly differentiated
Mitotic count > 20/2 mm2
Ki-67 > 20%

NET: neuroendocrine tumor; NEC: neuroendocrine carcinoma.