Table 1.

Baseline Characteristics of Patients Above and Below Median % Predicted Vo₂.

	% Predicted Peak Vo2, <Median of 48.6% n = 118	% Predicted Peak Vo2, ≥Median of 48.6% n = 117	p-Value
Baseline Characteristics
Age at CPET, years	50 ± 13	56 ± (9)	<0.001
Sex, % male	103 (87%)	90 (77%)	0.038
Ethnicity			0.066
Non-Hispanic White	91 (77%)	95 (81%)
Non-Hispanic Black	20 (17%)	22 (19%)
Hispanic	4 (3%)	0 (0%)
Other	3 (3%)	0 (0%)
Diabetic Pre-Transplant	52 (44%)	43 (37%)	0.25
Ischemic Etiology Pre-Transplant	51 (43%)	47 (40%)	0.64
PVD Pre-Transplant	8 (8%)	3 (3%)	0.12
COPD Pre-Transplant	9 (9%)	8 (8%)	0.82
PVR Pre-Transplant, dynes * s * cm−5	146 ± 114	128.5 ± 72	0.19
Serum Creatinine (mg/dL)	1.6 ± 0.9	1.5 ± 1.0	0.39
Daily Prednisone Dose, mg	3.5 ± 3.5	3.1 ± 3.0	0.40
Cyclosporine Use	18 (15.3%)	16 (13.8%)	0.75
CPET Parameters
Days from Transplant to CPET	88 ± 70	103 ± 79	0.12
Absolute Peak Vo2, mL O2/min	1095 ± 283	1528 ± 412	<0.001
% Predicted Peak Vo2	40 ± 6	62 ± 10	<0.001
O2 pulse, mL/beat	10 ± 3	12 ± 3	<0.001
Total Exercise Time, min	8 ± 3	9 ± 3	0.11
Peak Heart Rate, bpm	116 ± 17	125 ± 17	<0.001
Peak SBP, mmHg	149 ± 22	153 ± 22	0.18
Peak DBP, mmHg	81 ± 12	82 ± 11	0.71
Peak Respiratory Exchange Ratio	1.1 ± 0.1	1.1 ± 0.1	0.71
Hemoglobin at CPET, g/dL	13 ± 2	13 ± 2	0.23
Height, cm	176 ± 10	175 ± 10	0.35
Body Weight, kg	82 ± 19	88 ± 17	0.013
BMI at CPET, kg/m2	26 ± 5	29 ± 5	<0.001
Beta Blocker Use at CPET	25 (21%)	20 (17%)	0.46
Acute Cellular Rejection, %	35 (29.7%)	35 (29.9%)	0.97
Post-Transplant LVEF, %	64 ± 12	66 ± 7	0.34

Values are mean ± standard deviation or number (proportion). Acronyms: BMI, body mass index; COPD, chronic obstructive pulmonary disease; CPET, cardiopulmonary exercise test; DBP, diastolic blood pressure; SBP, systolic blood pressure; PVD, peripheral vascular disease; PVR, pulmonary vascular resistance; Vco₂, carbon dioxide output; Vo₂, oxygen consumption.