Table 3.
Variable | Univariate Analysis | Multivariate Analysis | ||
---|---|---|---|---|
p | OR (95% CI) | p | OR (95% CI) | |
Male | 0.07 | 0.63 (0.38–1.04) | ||
Age, per year | <0.001 | 1.04 (1.03–1.06) | 0.001 | 1.04 (1.02–1.06) |
Etiology | ||||
Skeletal muscle damage | Reference | Reference | ||
Cardiac muscle damage | 0.182 | 1.43 (0.85–2.42) | 0.008 | 2.76 (1.31–5.80) |
Hematologic disorder | <0.001 | 11.12 (4.76–25.96) | <0.001 | 9.47 (2.95–30.39) |
Hepatic decompensation | 0.001 | 6.95 (2.22–21.83) | 0.462 | 1.80 (0.38–8.56) |
Albumin, g/dL | <0.001 | 0.22 (0.15–0.33) | <0.001 | 0.28 (0.16–0.50) |
Bilirubin, mg/dL | <0.001 | 1.22 (1.10–1.36) | 0.190 | 1.09 (0.96–1.23) |
Creatinine, mg/dL | <0.001 | 1.87 (1.52–2.30) | <0.001 | 1.81 (1.42–2.31) |
PT-INR | <0.001 | 3.35 (2.15–5.23) | 0.591 | 1.17 (0.67–2.03) |
Peak AST | ||||
<1000 U/L | Reference | Reference | ||
<3000 U/L | 0.001 | 2.49 (1.45–4.29) | 0.006 | 2.94 (1.36–6.35) |
≥3000 U/L | <0.001 | 6.83 (3.34–13.95) | <0.001 | 9.61 (3.54–26.08) |
Abbreviation: OR, odds ratio; CI, confidence interval; PT-INR, prothrombin time- international normalized ratio; AST, aspartate aminotransferase.