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View full-text article in PMC

. 2023 Jan 3;24(1):814. doi: 10.3390/ijms24010814

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Robust shape memory polymer composite screws made of SMPU/HA/arginylglycylaspartate (RGD) are temperature-responsive to address the stiffness, bioactivity, and internal fixation capabilities of conventional screws limitations. The working schematic diagram of a SMPC screw: (A) size (1) and prototype (2) of the bone screw; (B) components in the SMPC screw; (C) working principle of a memory screw: (1) the screw was compressed at high temperature and then fixed at low temperature; (2) the programmed screw was implanted into the bone defect site by minimally invasive surgery; due to SME, the screw recovered to its original state and offered a supporting effect to the surrounding tissues; blue arrow: recovery force. The scale bars are 5 mm. (3) Representation of a single-slice micro–computed tomography (micro-CT) image after 12 weeks of implantation; blue imaginary line area indicates the SMPC screw. (Reproduced with permission [137]. Copyright 2020, Elsevier).