Table 4.
Univariate predictors of in-hospital mortality of patients with COVID-19.
| Parameter | OR | −95% CI | +95% CI | p-Value |
|---|---|---|---|---|
| Age (for every year) | 1.066 | 1.053 | 1.08 | <0.0001 |
| Age ≥ 70 | 4.408 | 3.232 | 6.011 | <0.0001 |
| Days of hosp. (n) | 0.968 | 0.95 | 0.987 | 0.0008 |
| AST (U/L) | 1.006 | 1.003 | 1.009 | <0.0001 |
| CRP (mg/L) | 1.005 | 1.003 | 1.007 | <0.0001 |
| D-dimer (µg/L) | 1.025 | 1.008 | 1.042 | 0.0035 |
| pH | 0.0026 | 0.0002 | 0.029 | <0.0001 |
| pCO2 (mmHg) | 1.021 | 0.999 | 1.043 | 0.0599 |
| Glucose (mg/dL) | 1.007 | 1.005 | 1.009 | <0.0001 |
| Creatinine (mg/dL) | 1.315 | 1.157 | 1.493 | <0.0001 |
| eGFR (mL/min/1.73 m2) | 0.974 | 0.969 | 0.979 | <0.0001 |
| Urea (mg/dL) | 1.027 | 1.022 | 1.033 | <0.0001 |
| RBC (million/mm3) | 0.769 | 0.634 | 0.933 | 0.0078 |
| WBC (thousand/µL) | 1.086 | 1.056 | 1.117 | <0.0001 |
| MCV (fL) | 1.039 | 1.016 | 1.063 | 0.0009 |
| PLT × 109 per L | 0.998 | 0.997 | 0.999 | 0.0065 |
| Neutrophils (%) | 1.054 | 1.04 | 1.067 | <0.0001 |
| Lymphocytes × 109 per L | 0.975 | 0.962 | 0.989 | 0.0003 |
| RDW-CV% | 1.078 | 1.016 | 1.145 | 0.0134 |
| NT-proBNP (pg/mL) | 1.097 | 1.067 | 1.128 | <0.0001 |
| Potassium (mg/dL) | 1.64 | 1.328 | 2.025 | <0.0001 |
| Procalcitonin (µg/L) | 1.017 | 0.997 | 1.038 | 0.0943 |
| Sodium (mg/dL) | 1.035 | 1.009 | 1.061 | 0.0078 |
| Computed tomography (%) | 1.027 | 1.02 | 1.034 | <0.0001 |
| Computed tomography ≥ 40% | 3.295 | 2.336 | 4.649 | <0.0001 |
| Serum ferritin (µg/L) | 1.00036 | 1.00015 | 1.00058 | 0.001 |
| SBP (mmHg) | 0.988 | 0.982 | 0.995 | 0.0006 |
| DBP (mmHg) | 0.969 | 0.958 | 0.98 | <0.0001 |
| SpO2 (%) | 0.923 | 0.904 | 0.942 | <0.0001 |
| SpO2 ≤ 87% | 4.625 | 3.152 | 6.786 | <0.0001 |
| PaO2/FiO2 (mmHg) | 0.994 | 0.993 | 0.995 | <0.0001 |
| Hypertension | 1.624 | 1.206 | 2.186 | 0.0014 |
| CAD | 1.538 | 1.091 | 2.17 | 0.0141 |
| HF | 3.198 | 2.281 | 4.483 | <0.0001 |
| Type 2 diabetes | 1.735 | 1.31 | 2.298 | 0.0001 |
| Oxygen therapy | 18.45 | 5.834 | 58.341 | <0.0001 |
| Antibiotic treatment | 7.185 | 3.853 | 13.397 | <0.0001 |
| Steroids | 2.556 | 1.629 | 4.01 | <0.0001 |
| Convalescent plasma | 0.44 | 0.319 | 0.606 | <0.0001 |
| Remdesivir | 0.341 | 0.223 | 0.522 | <0.0001 |
| NIV | 4.089 | 2.812 | 5.945 | <0.0001 |
| Ventilator therapy | 21.749 | 14.29 | 33.101 | <0.0001 |
RBC—red blood cells; WBC—white blood cells; CRP—C-reactive protein; PCT—procalcitonin; AST—aspartate transaminase; ALT—alanine transaminase; APTT—-activated partial thromboplastin time; PT—prothrombin time; NT-proBNP—N-terminal prohormone of brain natriuretic peptide; RDW—red blood cell distribution width; CAD—coronary artery disease; HF—heart failure; SBP—systolic blood pressure; DBP—diastolic blood pressure; SpO2—oxygen saturation at admission; PaO2/FiO2—oxygenation index; NIV—noninvasive ventilation.