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Second layer reflecting immune information in TCGA melanoma cohort. (A) Location of the 146 genes defining Layer 2 in the network. (B) Heatmap network of Layer 2 groups. (C) Comparison of functional node activities between defined groups. ****, p ≤ 0.0001; ***, p ≤ 0.001; **, p ≤ 0.01; *, p ≤ 0.05.
