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. 2023 Jan 6;18(1):e0279928. doi: 10.1371/journal.pone.0279928

Table 6. Medications with high node degrees.

Node (Medication) Degree Node (Medication) Degree Node (Medication) Degree
Vasopressin* 33 Phenylephrine** 18 Levofloxacin Dextrose 13
Norepinephrine 28 Potassium Chloride* 17 Insulin** 12
Fentanyl** 24 Vancomycin** 17 Etomidate 12
Midazolam* 23 Amiodarone* 15 Furosemide 11
Heparin* 18 Epinephrine* 15 Haloperidol 11
Calcium Chloride** 18 Piperacillin/Tazobactam Dextrose** 14 Lorazepam 10
Propofol* 18 Magnesium Sulfate 13
Milrinone* 18 Albumin 13

* Medications that contribute to the medication pairs associated with AKI but are not included on the list of nephrotoxins when used alone.

** Medication frequently prescribed, contributed in more than ten pairs of medications associated with AKI, and as single medications were also associated with AKI.