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. 2023 Jan 6;17(1):e0011006. doi: 10.1371/journal.pntd.0011006

Table 3. Minimum inhibitory concentrations (MIC) (μg/mL) of tested antimicrobials against tested B. pseudomallei and B. mallei strains.

Strain no. Species Amoxicillin/clavulanic acid ≤8/4 Sa,16/8 Ib and ≥32/16 Rc Ampicillin/sulbactam ≤8/4 S, 16/8 I and ≥32/16 R Ceftazidime ≤8 S, 16 I and ≥32 R Chloramphenicol ≤8 S, 16 I and ≥32 R Ciprofloxacin ≤1 S, 2 I and ≥4 R Doxycycline ≤4 S, 8 I and ≥16 R Imipenem ≤4 S, 8 I and ≥16 R Piperacillin ≤16 S, 32-64 I and ≥128 R trimethoprim-sulfamethoxazole ≤2/38 S, ≥4/76 R Meropenem ≤4 S, 8 I and ≥16 R Tigecycline ≤4 S, 8 I and ≥16 R
BM1343 B. mallei 0.75 1.5 0.75 0.5 0.23 0.064 0.125 1 0.23 0.125 0.125
BM1345 B. mallei 0.75 3 4 >256 8 2 0.25 3 >32 0.125 4
BM1347 B. mallei 0.5 1.5 0.75 1 0.25 0.047 0.125 4 <0.002 0.064 0.125
BM1349 B. mallei 1 1.5 1.5 12 1.5 0.32 0.125 1.5 <0.002 0.064 0.19
BM1352 B. mallei 3 4 2 3 0.25 0.064 0.19 3 0.016 0.125 0.094
BM1354 B. pseudomallei 3 4 0.75 8 1.5 3 0.5 0.5 1.5 0.5 16
BM1355 B. pseudomallei 1 2 0.5 1 3 0.25 0.38 1.5 2 0.5 1.5
BM1357 B. pseudomallei 3 4 1 8 3 1.5 0.25 2 0.25 0.38 6
BM1360 B. pseudomallei 1 1.5 0.5 16 4 2 0.19 1 1 0.38 4
BM1361 B. pseudomallei 12 3 0.75 48 6 4 1 1.5 1 0.5 32
BM649 B. pseudomallei 4 8 1.5 12 8 1.5 0.38 2 1.5 0.75 24

a S) susceptible; indicates there is a high probability of a favorable treatment outcome when treated with this antimicrobial(s)

b(I) Intermediate susceptible; indicates a uncertain outcome when treated with this antimicrobial(s)

c(R) Resistant, which indicates there is a low probability of a favorable treatment outcome when treated with this antimicrobial(s) (45).