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. 2022 Dec 25;12(1):154. doi: 10.3390/jcm12010154

Table 1.

Predisposing and precipitating conditions of spontaneous coronary artery dissection adapted from [18].

Predisposing Conditions Precipitating Conditions
Disorders of the connective tissue:
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    Fibromuscular dysplasia

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    Marfan syndrome

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    Ehlers–Danlos syndrome

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    Cystic necrosis of the media

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    Systemic inflammation

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    Systemic lupus erythematosus

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    Rheumatoid arthritis

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    Churg-Strauss syndrome

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    Chron’s disease

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    Polyarteritis nodosa

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    Sarcoidosis

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    Pregnancy

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    Prepartum (within 6 weeks of delivery)

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    Postpartum with late occurrence (from 6 weeks to 12 months from childbirth)

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    Postpartum with very late occurrence (12 to 24 months from childbirth)

Coronary spasm
Intense physical exercise (isometric or aerobic activity)
Intense emotional stress
Childbirth and labor of childbirth
Intense Valsalva-like activity (retching, vomiting, coughing, bowel movements)
Drugs (cocaine, amphetamines, methamphetamines)
Hormonal therapies (injection of β-chorionic gonadotropins, corticosteroid injections)

SCAD: Spontaneous coronary artery dissection.