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. 2022 Dec 27;12(1):206. doi: 10.3390/jcm12010206

Table 1.

Demographic and clinical characteristics of the 205 HD patients.

Age of Motor Symptom Onset (Years) CAG Repeats Age at Diagnosis (Years) DD (Years) Duration (Years)
Mean (SD) Range Mean (SD) Range Mean (SD) Range Mean (SD) Range Mean (SD) Range
Total (n = 205) 41.8 (10.0) 17–69 45.2 (4.5) 38–67 45.7 (11.1) 18–78 4.3 (3.8) 0–20 5.2 (3.9) 0–20
Male (n = 84) 42.1 (10.5) 18–67 45.2 (4.7) 38–67 46.6 (11.6) 22–78 4.7 (4.1) 0–18 5.5 (4.1) 0–18
Female (n = 121) 41.6 (9.6) 17–69 45.2 (4.4) 38–61 45.2 (10.7) 18–74 4.0 (3.6) 0–20 5.1 (3.7) 0–20
Juvenile HD (n = 4) 18.1 (1.40) 17–20 53.5 (12.40) 43–67 22.10 (3.1) 18–25 4.0 (2.0) 1–5 4.50 (1.0) 3–5
Adult HD (n = 193) 41.4 (8.6) 20–58 45.1 (4.2) 38–61 45.3 (9.80) 19–70 4.1 (3.6) 0–19 5.2 (3.7) 0–19
Elderly-onset HD (n = 8) 63.5 (3.1) 61–69 43.0 (1.2) 42–45 68.2 (5.4) 62–78 7.4 (7.3) 1–20 7.4 (7.3) 1–20
Positive family history (n = 162) 40.1 (9.4) a 17–67 45.7 (4.6) b 38–67 43.6 (10.1) d 18–69 3.8 (3.4) e 0–19 4.8 (3.5) f 0–19
Paternal inheritance (n = 86) 38.9 (9.7) 17–67 46.4 (5.2) 39–67 42.2 (10.2) 18–69 3.3 (2.8) 0–12 4.38 (2.9) 0–15
Maternal inheritance (n = 76) 41.4 (9.0) 19–62 44.9 (3.8) 38–57 45.1 (9.8) 19–69 4.4 (4.0) 0–19 5.2 (4.0) 0–19
Negative family history (n = 43) 48.4 (9.4) a 28–69 43.2 (3.3) b 38–53 53.9 (10.7) d 31–78 5.8 (4.8) e 0–20 7.0 (4.8) f 1–20
Motor (n = 188) 41.4 (9.7) 17–67 45.2 (4.5) c 38–67 45.5 (10.8) 18–78 4.2 (3.7) 0–19 5.2 (3.8) 0–19
Cognitive (n = 5) 49.6 (7.5) 42–62 43.4 (1.1) c 42–45 50.1 (7.2) 42–62 3.8 (1.4) 2–6 3.7 (1.4) 2–6
Psychiatric (n = 12) 45.6 (13.5) 25–69 45.8 (5.8) 40–57 47.8 (15.3) 19–73 5.9 (6.0) 0–20 6.9 (5.4) 0–20

a–f: statistically significant was found between the groups (p < 0.05). DD: diagnostic delay; SD: standard deviation.