Table 2.
Motor measures by the Unified Huntington’s Disease Rating Scale (UHDRS) scores of 205 HD patients.
UHDRS I (Total Motor Score) |
UHDRS II (FAS) |
UHDRS III (Independence Assessment) |
UHDRS IV (TFC) |
|
---|---|---|---|---|
Total (205) | 40.5 (19.0) | 18.3 (5.4) | 82.9 (15.8) | 8.6 (3.4) |
Male | 43.2 (20.1) | 18.5 (5.5) | 82.2 (16.5) | 8.6 (3.4) |
Female | 38.5 (18.0) | 18.2 (5.4) | 83.4 (15.3) | 8.6 (3.4) |
Juvenile HD (4) | 22.0 (1.4) a | 17.5 (7.1) | 93.3(5.8) c | 11.3 (0.6) |
Adult HD (193) | 40.4 (18.8) a | 18.5 (5.2) | 84.1 (13.8) c | 8.6 (3.4) |
Elderly-onset HD (8) | 54.4 (11.4) a | 14.1 (8.0) | 70.6 (21.3) c | 6.8 (4.2) |
Positive family history (162) | 40.3 (19.0) | 19.4 (4.2) b | 84.0 (15.2) d | 8.8 (3.3) |
Paternal inheritance (86) | 41.0 (18.4) | 19.2 (4.3) | 84.6 (12.4) | 8.7 (3.1) |
Maternal inheritance (76) | 40.4 (21.3) | 19.4 (4.4) | 83.2 (17.8) | 8.8 (3.5) |
Negative family history (43) | 41.2 (19.1) | 16.3 (6.1) b | 78.9 (17.4) d | 7.8 (3.7) |
Motor (188) | 40.4 (19.2) | 18.4 (5.4) | 83.2 (15.6) | 8.6 (3.4) |
Cognitive (5) | 43.2 (24.0) | 17.3 (3.2) | 74.0 (27.0) | 6.6 (3.1) |
Psychiatric (12) | 41.1 (14.2) | 18.6 (3.0) | 82.7 (12.3) | 8.3 (2.5) |
a–d: statistically significant was found among the groups (p < 0.05). UHDRS: Unified Huntington’s Disease Rating Scale; FAS: functional assessment scores; TFC: total functional capacity.