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Sensitivity to cisplatin treatment in RH30 cell lines after HMGB1 knockdown. RH30 transduced with shHMGB1 lentivirus were treated with cisplatin (cDDP) at 5, 10 and 20 µM over 48 h and percentage of cell viability was compared versus RH30 transduced with shControl lentivirus. ** p < 0.01, *** p < 0.001, Student t test. The data from one of two independent experiments are shown.
