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. 2022 Dec 30;28(1):297. doi: 10.3390/molecules28010297

Figure 2.

Figure 2

Figure 2

The effect of L. plantarum administered alone or in combination with MTX on the activity of GGT in the spleen (a) and joint (b) on day 28. CO—healthy control group, AA—group of controls with adjuvant arthritis (AA), CO-LB—a control group of healthy animals administered with L. plantarum (LB), AA-LB—group of animals with AA administered with LB, AA-MTX—rats with AA treated with methotrexate (MTX), AA-LB-MTX—group of rats with AA receiving combinational therapy of MTX and LB. Values are expressed as mean ± S.E.M. Statistical significance was evaluated by applying ANOVA for independent variables: *** p < 0.001 vs. CO; +++ p < 0.001 and ++ p <0.01 vs. AA.