Table 2.

Antiproliferative effect of NPs and the corresponding reference drugs, CBD (1), N-desacetyl thiocolchicine (2), podophyllotoxin (3), and paclitaxel (4).

	GI50 (μM) a
	MSTO-211H	HT-29	HepG2
1	10.1 ± 1.8	10.1 ± 0.5	13.3 ± 1.7
2	0.014 ± 0.001	0.021 ± 0.003	0.021 ± 0.003
6A	12.1 ± 1.9	7.2 ± 0.3	>20
6B	1.1 ± 0.2	1.4 ± 0.5	3.9 ± 0.7
3	0.012 ± 0.001	0.013 ± 0.002	0.018 ± 0.003
7A	4.8 ± 0.8	6.1 ± 0.9	14.5 ± 1.7
7B	2.5 ± 0.7	2.6 ± 0.1	2.6 ± 0.6
4	0.0035 ± 0.0002	0.0035 ± 0.0005	0.025 ± 0.006
8A	9.5 ± 0.5	>20	>20
8B	0.43 ± 0.01	2.5 ± 0.2	4.8 ± 0.7

^a GI₅₀ values are the mean ± SD of at least three independent experiments in duplicate.