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Antigen-specific, MHC-restricted CTL response in volunteer 16 (HLA-A*01). Immune PBMC from volunteer 16 were stimulated with peptide PfCSP 3D7 310-319. Cytolytic activity was then assessed in a CTL assay at an 80:1 effector/target ratio using autologous and HLA-mismatched B-LCL transiently transfected targets with a plasmid expressing PfCSP-encoding DNA (2510) or vector control DNA (1020) as a negative control.
