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. 2022 Dec 29;28(1):287. doi: 10.3390/molecules28010287

Table 4.

Pro-apoptotic activity of selected benzothiazole derivatives on HaCat and Colo-38 cell lines.

HaCat Cell Line
Sample Early Apoptosis (%) Late Apoptosis (%) Dead (%)
Vehicle (-) 1.93 5.89 1.22
BZTcin4 (5 µM) 1.83 3.05 0.41
BZTcin4 (10 µM) 1.13 15.56 1.96
BZTcin5 (50 µM) 2.29 3.73 0.19
BZTcin5 (100 µM) 1.84 5.00 0.20
Colo-38 Cell Line
Sample Early Apoptosis (%) Late Apoptosis (%) Dead (%)
Vehicle (-) 2.01 5.98 0.91
BZTcin2 (5 µM) 1.70 16.90 2.05
BZTcin2 (50 µM) 1.85 29.90 4.45
BZTcin4 (5 µM) 3.85 8.50 1.00
BZTcin4 (10 µM) 3.20 8.00 1.35
BZTcin5 (10 µM) 1.80 21.40 3.75
BZTcin5 (50 µM) 1.40 16.25 3.50