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. 2022 Dec 21;28(1):43. doi: 10.3390/molecules28010043

Figure 3.

Figure 3

Alignment of the protein sequences of plant NPMTs and bacterial MTs. The plant species and accession numbers of these MTs are listed in Table 1. Plant NPMTs include cation-dependent SbCCoAOMT, cation-independent MtHI4′OMT, SABATH CrLAMT, and CcDXMT, and BIA TfPavNMT, in comparison to the bacterial MT within Class I bacterial LiOMT (Leptospira interrogans, WP_000087781), and non-Class I bacterial SvAviRbMT (Streptomyces viridochromogenes, WP_003998250). The red boxes indicate the glycine-rich Rossmann fold consensus sequences with 0–3 mismatches. The amino acid residues highlighted in blue are highly conserved, those in green are conserved, and those in yellow are moderately conserved. “*” represents every 10th amino acid after each numerical indicator.