Table 2.
Longitudinal changes of HBsAg level during treatment.
| Parameter | R group n=45 | NR group n=33 | P-value |
|---|---|---|---|
| HBsAg level (IU/mL) | |||
| Baseline | 72.04 (3.45, 164.75) | 77.67 (19.16, 167.95) | 0.602 |
| Week12 | 6.75 (0.77, 36.82) | 39.52 (7.99, 126.65) | 0.003* |
| Week24 | 0.96 (0.13, 5.42) | 19.83 (0.70, 71.14) | 0.001* |
| Week36 | 0.40 (3.45, 1.24) | 6.86 (0.76, 76.00) | <0.001* |
| Week48 | 0.11 (0.00, 0.66) | 7.83 (0.58, 64.09) | <0.001* |
| Week60 | 0.03 (0.00, 0.57) | 3.13 (0.91, 36.16) | <0.001* |
| Week72 | 0.00 (0.00, 0.08) | 7.74 (1.26, 58.30) | <0.001* |
| Week84 | 0.00 (0.00, 0.06) | 16.71 (2.29, 76.25) | <0.001* |
| Week96 | 0.00 (0.00, 0.00) | 10.18 (4.73, 58.01) | <0.001* |
| HBsAg decline from baseline (log10 IU/ml) | |||
| Week12 | 0.60 ± 0.13 | 0.24 ± 0.10 | 0.031* |
| Week24 | 1.12 ± 0.16 | 0.58 ± 0.14 | 0.019* |
| Week36 | 1.24 ± 0.22 | 0.79 ± 0.18 | 0.124 |
| Week48 | 1.43 ± 0.15 | 0.73 ± 0.16 | 0.002* |
| Week60 | 1.31 ± 0.18 | 0.84 ± 0.16 | 0.059 |
| Week72 | 1.38 ± 0.17 | 0.76 ± 0.17 | 0.017* |
| Week84 | 1.41 ± 0.18 | 0.50 ± 0.23 | 0.002* |
| Week96 | 1.39 ± 0.14 | 0.56 ± 0.14 | <0.001* |
R group (Responder group); NR group (Non-Responder group).
* p <0.05 .