Table 2. Complications Related to HSCT and Acute Pancreatitis in HSCT Patients, Stratified by the Presence of AP.
Without pancreatitis | With pancreatitis | P-value | |
---|---|---|---|
Etiologies/complications related to HSCT | |||
Myelodysplastic syndrome | 9,375 (6.73) | 50 (5.85) | 0.641 |
Lymphoid leukemia | 11,595 (8.33) | 120 (14.04) | 0.009 |
Myeloid leukemia | 26,095 (18.74) | 155 (18.13) | 0.842 |
Hodgkin’s lymphoma | 4,430 (3.18) | 20 (2.34) | 0.532 |
Non-Hodgkin’s lymphoma | 3,505 (2.52) | 15 (1.75) | 0.526 |
Bone marrow failure | 30 (0.02) | 0 (0) | 0.846 |
HLH | 290 (0.21) | 0 (0) | 0.569 |
Thalassemia | 290 (0.21) | 0 (0) | 0.57 |
Sickle cell | 1,590 (1.14) | 25 (2.92) | 0.061 |
Metabolism error | 210 (0.15) | 0 (0) | 0.639 |
Primary immunodeficiency | 5,710 (4.1) | 35 (4.09) | 0.997 |
Graft-versus-host disease | 19,390 (13.92) | 185 (21.64) | 0.005 |
Hemolytic uremic syndrome | 130 (0.09) | 0 (0) | 0.726 |
Conditions related to acute pancreatitis | |||
Cholangitis | 660 (0.47) | 55 (6.43) | < 0.001 |
Choledocholithiasis | 1,680 (1.21) | 135 (15.79) | < 0.001 |
Other biliary disorders | 1,680 (1.21) | 55 (6.43) | < 0.001 |
Hypertriglyceridemia | 1,025 (0.74) | 90 (10.53) | < 0.001 |
Hypercalcemia | 2,025 (1.45) | 25 (2.92) | 0.112 |
Systemic lupus erythematosus | 455 (0.33) | a | 0.057 |
Diabetic ketoacidosis | 255 (0.18) | 25 (2.92) | < 0.001 |
Cystic fibrosis | 50 (0.04) | 0 (0) | 0.843 |
Alcohol use | 1,805 (1.3) | 50 (5.85) | < 0.001 |
Abdominal trauma | 225 (0.16) | 0 (0) | 0.607 |
Anomalies of the pancreas | 0 (0) | 20 (2.34) | < 0.001 |
Percutaneous biliary procedures | 25 (0.02) | 0 (0) | 0.881 |
ERCP | 285 (0.2) | 60 (7.02) | < 0.001 |
aValues less than 11, not to be reported as per HCUP data user agreement (DUA). AP: acute pancreatitis; HSCT: hematopoietic stem cell transplantation; HLH: hemophagocytic lymphohistiocytosis; ERCP: endoscopic retrograde cholangiopancreatography.