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. 2022 Dec 23;13:1037214. doi: 10.3389/fimmu.2022.1037214

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Copyright © 2022 Räuber, Willison, Korsen, Kölsche, Golombeck, Plaack, Schüller, Huntemann, Rolfes, Schroeter, Nelke, Regner-Nelke, Förster, Ringelstein, Barnett, Hartung, Aktas, Albrecht, Ruck, Melzer, Meuth and Kremer

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Study design illustrating patient cohorts and the time course of performed analyses. BL, baseline; DMT, disease modifying therapy; HC, controls without MS; IFN, interferon; Ig, immunoglobulin; MS, multiple sclerosis; N, nucleocapsid; NAT, natalizumab; OCR, ocrelizumab; pwMS, patients with MS; pv2/3/4, post second/third/fourth vaccination; S, spike; SARS-CoV-2, severe acute respiratory syndrome; S1P, sphingosine 1-phosphate receptor modulator; V, visit; vacc, vaccination; w/o, without. Created with BioRender.com.