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. 2022 Sep 13;48(1):295–304. doi: 10.1007/s11064-022-03748-0

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Typical I-V recording of the current obtained in a SH-SY5Y cell, elicited by a ramp protocol from − 100 mV to + 100 mV and activated by AITC in control conditions and the presence of PTX and HC-030. B Typical I–V relationship of the AITC-induced current in SH-SY5Y cells in control conditions and the presence of PTX and HC-030. *Denotes significant differences. C Typical current (I) recording at − 60 mV in the presence of AITC, AITC + PTX and AITC + PTX + HC030, as indicated. D Comparison between the mean maximal normalized current recorded at − 60 mV and + 60 mV under the same conditions. n = 8 in all cases. *Denotes significance (p = 0.02)