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. 2022 Sep 13;48(1):295–304. doi: 10.1007/s11064-022-03748-0

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Recordings of single-channel activity and corresponding amplitude histogram of single-channel currents measured at − 60 mV in inside-out patches from SH- SY5Y cells under basal conditions (A), in the presence of AITC (B), and in the presence of AITC and PTX (C). D Comparison of the mean open probability (Po) in 8 different patches in the conditions described in A–C, as indicated. *Denotes significant increase (p = 0.01) in comparison to basal conditions. **Denotes a significant increase (p = 0.01) in comparison to the control. E Comparison of the mean inward and outward conductances in 8 different patches in the conditions described in A–C, as indicated. Conductances were calculated from linear regressions of the corresponding I–V relationships. *Denotes significant increase (p = 0.01) in comparison to inward current control or to outward current control