Table 4.
Treatment-related adverse events in total population
| Adverse events | Any grade (%) | Grade ≥ 3 (%) |
|---|---|---|
| Diarrhoea | 34 (85.0) | 10 (25.0) |
| Leukopenia | 17 (42.5) | 5 (12.5) |
| Neutropenia | 15 (37.5) | 6 (15.0) |
| Fatigue | 15 (37.5) | 0 |
| Vomiting | 13 (32.5) | 1 (2.5) |
| Nausea | 5 (12.5) | 0 |
| Hand-foot syndrome | 4 (10.0) | 0 |
| Aspartate aminotransferase increase | 4 (10.0) | 1 (2.5) |
| Anorexia | 3 (7.5) | 0 |
| Alanine aminotransferase increase | 2 (5.0) | 0 |
| Anemia | 2 (5.0) | 0 |
| Peripheral neurotoxicity | 2 (5.0) | 0 |
| Rash | 1 (2.5) | 0 |
| Thrombocytopenia | 1 (2.5) | 1 (2.5) |