Table 3.
Hazard ratio (95% confidence interval) for distal radius fracture in the gout and control groups with subgroup analyses according to age and sex.
| Characteristics | No. of Distal Radius Fracture/ No. of Participants |
Follow-Up Duration, Person-Years |
Incidence Rate, Per 1000 Person-Years |
Hazard Ratios for Distal Radius Fracture | |||
|---|---|---|---|---|---|---|---|
| Crude † | p | Adjusted ‡ | p | ||||
| Total participants (n = 81,525) | |||||||
| Gout | 277/16,305 | 97,976 | 2.8 | 1.06 (0.93–1.21) | 0.401 | 1.06 (0.93–1.21) | 0.413 |
| Control | 1052/65,220 | 392,452 | 2.7 | 1 | 1 | ||
| Age < 60 years old (n = 44,945) | |||||||
| Gout | 142/8989 | 61,058 | 2.3 | 1.09 (0.91–1.31) | 0.367 | 1.08 (0.90–1.31) | 0.411 |
| Control | 525/35,956 | 245,087 | 2.1 | 1 | 1 | ||
| Age ≥ 60 years old (n = 36,580) | |||||||
| Gout | 135/7316 | 36,918 | 3.7 | 1.03 (0.85–1.24) | 0.774 | 1.03 (0.85–1.25) | 0.766 |
| Control | 527/29,264 | 147,365 | 3.6 | 1 | 1 | ||
| Males (n = 69,705) | |||||||
| Gout | 169/13,941 | 83,807 | 2.0 | 1.04 (0.88–1.23) | 0.666 | 1.06 (0.89–1.26) | 0.519 |
| Control | 652/55,764 | 335,341 | 1.9 | 1 | 1 | ||
| Females (n = 11,820) | |||||||
| Gout | 108/2364 | 14,169 | 7.6 | 1.09 (0.88–1.35) | 0.414 | 1.05 (0.85–1.31) | 0.645 |
| Control | 400/9,456 | 57,111 | 7.0 | 1 | 1 | ||
Stratified Cox proportional hazard model, Significance at p < 0.05 with Bonferroni correction. † Models were stratified by age, sex, income, and region of residence. ‡ Adjusted for total cholesterol, systolic blood pressure, diastolic blood pressure, fasting blood glucose, obesity, smoking, alcohol consumption, osteoporosis history and Charlson comorbidity index score.