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. 2023 Jan 1;15(1):221. doi: 10.3390/nu15010221

Figure 1.

Figure 1

PERMANOVA statistical test showed a significant change between control and HLA-DQ2/DQ8 positive-RPL women in (p = 0.037, R2 = 0.109) in endometrial samples (Shannon diversity). No significant differences were observed between RPL women independent of the HLA-DQ2/DQ8 state (p = 0.900) (A,B). Differences in the microbial population between healthy control and women with CD predisposition were assessed using weighted Unifrac beta diversity. The obtained distance matrix was represented as PCoA, showing a clusterization among the three studied groups (C). Legend: CTR = control; Low = HLA-DQ2/DQ8 negative-RPL women; High = HLA-DQ2/DQ8 positive-RPL women. ** significantly different.