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. 2022 Dec 21;15(1):30. doi: 10.3390/nu15010030

Table 1.

Bias assessment.

Study NIH Criteria
Hu et al., 1999 [22] Praagman et al., 2016 [32] Praagman et al., 2016 [31] Zong et al., 2016 [33] Praagman et al., 2019 [30]
Yes Yes Yes Yes Yes (1) Clear objective research questions
Yes Yes Yes Yes Yes (2) Defined study population
Yes Yes Yes Yes Yes (3) Participant of >50% of eligible persons
Yes Yes Yes Yes No (4) Consistent subject selection/recreation and predetermined exclusion/inclusion criteria applied
NR/UTD NR/UTD NR/UTD NR/UTD NR/UTD (5) Sample size justification/stats provided
Yes Yes Yes Yes Yes (6) Exposures measured prior to outcome
Yes Yes Yes Yes Yes (7) Appropriate timeframe to assess desired exposure and outcome
Yes Yes Yes Yes Yes (8) For variable exposures, different levels were assessed
Yes Yes Yes Yes Yes (9) Clearly defined independent variable consistently implemented
Yes No No Yes No (10) Repeat measure of exposure over time
Yes Yes Yes Yes No (11) Clearly defined dependent variables consistently implemented
Yes NR/UTD NR/UTD Yes Yes (12) Blinded outcome assessors
NR/UTD NR/UTD NR/UTD NR/UTD No (13) Loss to follow up < 20%
Yes Yes Yes Yes No (14) Confounding variables identified and adjusted statistically

Table created using Study Quality Assessment Tools | NHLBI, NIH. https://www.ncbi.nlm.nih.gov/pubmed/NR/UTD (Accessed on 12 October 2022), not reported or unable to determine.