FIG. 6.

Mortality (A and B) and development of TE (C) in T. gondii-infected, sulfadiazine-treated nude mice with adoptive transfer of immune T cells. Nude mice (A, five mice in each group; B, seven or eight mice in each group; C, three or four mice in each group) were infected with 10 cysts of the ME49 strain perorally and treated with sulfadiazine for 3 weeks beginning 7 days after infection. Nine and 2 days before discontinuation of sulfadiazine treatment, mice received an intravenous injection of 10⁷ immune T cells (A) or either CD4⁺ or CD8⁺ subsets of immune T cells (B and C) purified from immune spleen cells (see Materials and Methods). The data shown are representative of two separate experiments (A and C) or pooled from two independent experiments (B).