Figure 7.
Effects of DCA vehicle (Non-IBS), 4 mmol/L DCA (IBS), L. fermentum (109 CFU) (L. ferm), Gabapentin at 70 mg/kg (GBP) and Rifaximin at 150 mg/kg (RFX) administration on colonic tissue. (a) Representative sections of the distal colon analyzed by hematoxylin and eosin staining (scale bar = 20 μm). (b) Histopathological scores of inflammation cell infiltration, depth of lesions, destruction of crypts, width of lesions and crypt damage. Data are expressed as means ± SEM (n = 10). Groups with different letters statistically differ (p < 0.05).