Figure 9.
Impact of probiotic administration on microbiome diversity of DCA vehicle (Non-IBS), 4 mmol/L DCA (IBS), L. fermentum (109 CFU) (L. ferm)-, Gabapentin at 70 mg/kg (GBP)- and Rifaximin at 150 mg/kg (RFX)-treated rats. (a) Alpha microbiota diversity indexes determined by Illumina sequencing: Observed species, Shannon and Simpson indexes, ACE and PD-Whole indicator. (b) β-diversity calculated by principal coordinate analysis score plot. Data are presented as mean ± SEM. Bars with different letters statistically differ (p < 0.05).