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. 2022 Dec 21;15(1):24. doi: 10.3390/nu15010024

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Impact of L. fermentum administration on microbiota composition of DCA vehicle (Non-IBS), 4 mmol/L DCA (IBS)-, L. fermentum (10⁹ CFU) (L. ferm)-, Gabapentin at 70 mg/kg (GBP)- and Rifaximin at 150 mg/kg (RFX)-treated rats. (a) Distribution histogram of relative abundance of phylum taxa. (b) Bacillota/Bacteroidota (called F/B) ratio in each experimental group. (c) Venn diagram showing the number of OTUs unique and common to each group. (d) Taxonomic signatures at genus level. Data are presented as mean ± SEM. Bars with different letters are statistically different (p < 0.05).