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Titers of IgA antibody to FimA in serum at termination of the experiment in rats coimmunized with recombinant S. gordonii and infected with P. gingivalis. Animals were immunized at weeks 0 and 3 with recombinant S. gordonii and infected at week 6 with P. gingivalis by oral gavage (three doses given at 48-h intervals at 1012 CFU per dose). Bars indicate antibody titers (mean ± standard error, n = 8) in each group. ***, P < 0.001 versus the control, RFU, relative fluorescence units.
