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. 2023 Jan 2;28(1):366. doi: 10.3390/molecules28010366

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of purpurin on CD4+ and CD8+ T cells, and FOXP3 contents. (A) The ratio of CD4+/CD8+ estimated using flow cytometry. (a) AIA group, (b) Dex group, (c) high-dose purpurin group, (d) medium-dose purpurin group, and (e) low-dose purpurin group. (B) Immunohistochemical staining of FOXP3 in the spleen tissue of rats in each group (magnification: 100-fold). (C) The optical density (OD) value of each group. Dex: dexamethasone; AIA: adjuvant-induced arthritis; Data are represented as mean ± SD. ^### p < 0.001 vs. control, *** p < 0.001 vs. model, n = 6 in each group.